However, testosterone in physiologic doses may even be beneficial in sufferers with angina , have greater ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood flow in men with established coronary artery disease . Therefore, an interaction of endogenous factors of the patient’s danger profile in addition to the testosterone dosing may be problems with whether opposed occasions happen. Erythrocytosis has been reported as a potential effect of testosterone, which could be helpful in sufferers with anemia.
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- Effects of testosterone on coronary vasomotor regulation in men with coronary coronary heart disease.
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Patients also may be taking concomitant stimulants, such as ephedra, which can confound data and the potential for adverse occasions. It is likely that the frequency of cardiac events is underreported within the medical literature. Moreover, testosterone has been used in the remedy of lowered muscle mass and bone density in addition to anemia. The position testosterone could play in the growth of cardiovascular disease has increasingly turn into the subject of current interest . Supraphysiologic doses of anabolic-androgenic steroids , which include greater than 30 natural and synthetic derivatives of testosterone, might trigger a large spectrum of clinical sequalae. Supplemental or physiologic doses of testosterone have seen expanded use in medical apply just lately. Other widespread potential antagonistic results embody infertility, hepatotoxicity, psychological abnormalities, and gynecomastia .
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